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FORMULA-509 probes salvage radiation and gonadotropin-releasing hormone routine

March 16, 2023

5 min watch

Nguyen studies consulting for Bayer, Blue Earth Diagnostics, Boston Scientific, Janssen Oncology and Myovant Sciences; and receiving analysis funding from Astellas Pharma, Bayer and Janssen.

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On this video, Paul Nguyen, MD, a genitourinary radiation oncologist at Dana-Farber Most cancers Institute, discusses the FORMULA-509 trial he co-presented at ASCO Genitourinary Cancers Symposium.

The research examined sufferers with a rising PSA after radical prostatectomy who had no less than one unfavorable danger issue, and who acquired salvage radiation and 6 months of a gonadotropin-releasing hormone agonist.

“What I feel we will say now could be for a affected person as we speak, utilizing the FORMULA-509 routine is a really engaging various to having to elongate the length of hormone remedy to 24 months,” Nguyen mentioned.


  • Nguyen P, et al. FORMULA-509: A multicenter randomized trial of post-operative salvage radiotherapy (SRT) and 6 months of GnRH agonist with or with out abiraterone acetate/prednisone (AAP) and apalutamide (Apa) post-radical prostatectomy (RP). Introduced at: ASCO Genitourinary Cancers Symposium; ; Feb. 16-18, 2023; San Francisco.


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