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HomeMedicalIn vivo OCT elastography confirmed capability to distinguish keratoconic from wholesome corneas

In vivo OCT elastography confirmed capability to distinguish keratoconic from wholesome corneas

March 16, 2023

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Torres-Netto E. Excessive-resolution OCT elastography assessing biomechanics in regular and keratoconus topics. Offered at: European Society of Cataract and Refractive Surgeons winter assembly; March 10-12, 2023; Vilamoura, Portugal.

Torres-Netto reviews no related monetary disclosures.

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Key takeaways:

  • Excessive-resolution OCT elastography reveals potential in diagnosing and monitoring keratoconus.
  • This technique can also supply the chance to find out the impression of corneal cross-linking.

VILAMOURA, Portugal — In a examine carried out for the primary time in vivo, high-resolution OCT elastography confirmed the potential to grow to be an extra diagnostic and monitoring software for keratoconus.

On the European Society of Cataract and Refractive Surgeons winter assembly, Emilio Torres-Netto, MD, PhD, confirmed how the data supplied by this novel know-how differentiated keratoconic corneas from wholesome corneas.


“Excessive-resolution OCT elastography makes use of OCT, a know-how many people have available in clinics. It permits for noninvasive analysis of biomechanical adjustments below close-to-physiologic circumstances,” he mentioned.

Elastography, he mentioned, depends on speckle monitoring to estimate relative movement of subsurface buildings imaged below totally different utilized stresses. The interface pictures acquired by OCT will be modeled roughly within the type of a convolution.

The Sabine Kling OCT elastography prototype was utilized in a gaggle of eyes with keratoconus and a gaggle of wholesome eyes, making use of a stress variation of –6 mm Hg by means of a custom-built set of goggles.

“Over 2 seconds, a number of pictures of the cornea had been obtained, after which the displacement between these pictures was calculated,” Torres-Netto mentioned. “What we may observe is that in wholesome eyes, the posterior and anterior a part of the cornea, whenever you cut back the stress, transfer as a complete. In keratoconus corneas, they transfer in several instructions, one ahead and one backward. This distinction between a wholesome and a keratoconus cornea is detectable in vivo with OCT in simply 2 seconds.”

This technique will open new horizons, he mentioned, not only for the prognosis and monitoring of keratoconus in progressive instances, however to find out the results of corneal cross-linking.



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